Chronic kidney disease (CKD) is an emerging public health challenge in Nigeria, with increasing prevalence placing significant strain on healthcare systems. This study explores the demographic characteristics and health-related factors among a sample of 150 respondents. It details the distribution of participants by age, gender, ethnicity, and marital status, and examines the prevalence of CKD diagnosis throughout 2021, noting possible seasonal trends. A high prevalence of comorbid conditions and symptoms associated with CKD was identified, underscoring the necessity for early detection, comprehensive management, and targeted public health strategies. The overall prevalence of CKD among individuals attending the dialysis unit was notably high at 90.7%. Key risk factors identified include obesity (90%), heart disease (90%), prior history of CKD (90%), inherited kidney disorders (90%), past kidney damage (100%), diabetes (90%), and hypertension (90%). Predominant clinical symptoms reported were fatigue (100%), hypertension (90%), loss of appetite (80%), malaise (80%), reduced urine output (70%), pulmonary oedema (80%), and wasting (100%). The study found no significant association between age or gender and CKD prevalence among youths in the dialysis unit. The vital role of nurses in patient education, advocacy, and holistic care is emphasized. The study acknowledges limitations such as sample size and possible biases. Recommendations stress the importance of health education, integrated care models, public health interventions, enhanced nursing training, and further research. Suggested future research directions include longitudinal studies, examination of seasonal effects, comparative analyses, qualitative investigations, and assessments of socioeconomic influences.